"I didn't make many good pitches and they made me pay for it," said Lohse, who lasted just five innings, giving up seven runs, and was drummed out in a four-run New York sixth.
On the upside, Albert Pujols homered for the second day in a row after not homering for 17 games.
And Jason Isringhausen, the former closer who was mopping up Sunday, mowed down the Mets' 3-4-5 hitters in order in a spotless eighth. He may be in line for more significant roles with the Cardinals or may be more attractive for a possible trade, which he would have to approve.
METS 9, CARDINALS 1: The Cardinals didn't seem to have much jump after a five-hour, nine-minute, 14-inning win on Saturday, but Johan Santana had something to do with that. The Cardinals had just one runner in scoring position other than Albert Pujols' seventh-inning homer, his 20th.
NOTES AND QUOTES
--The Cardinals finally gave up on disappointing RHP Anthony Reyes, dealing him to Cleveland for minor leaguer Luis Perdomo, who has excelled in relief at both the Class A and Class AA levels this season. Perdomo, 24, was assigned to Class AA Springfield.
--RHP Chris Carpenter, who had Tommy John elbow surgery and hasn't pitched in the majors since Opening Day of last season, will start Wednesday at Atlanta.
--RHP Joel Pineiro has only a 1-2 record and 10 no-decisions to show for his last 13 starts and has had trouble pitching during his past six innings. He has given up 20 hits over his last 10 innings, including a 10-hit allotment in four innings on Saturday.
--CF Rick Ankiel sat out Sunday with an abdominal strain and is classified as "day to day."
--LHP Randy Flores, who has had control problems much of the season, didn't walk anybody on Sunday but he did give up four base hits among the six batters he faced.
--RHP Mitchell Boggs, who logged 95 pitches in losing Friday's game, pitched an inning of relief Sunday, leading to speculation that he will be replaced on the roster by the start of Monday.
BY THE NUMBERS: 23 and 25 -- Number of bullpen losses and blown saves, respectively, for the Cardinals, as they hit the two-thirds mark of the season.
QUOTE TO NOTE: "Once I start spinning the ball with authority, then I'm pretty close to returning." -- RHP Adam Wainwright, on the rehabilitation trail after suffering a sprained middle finger on his pitching hand.